Tracing the Pathogenesis of Type 1 Diabetes: A Report on the 44th Annual Meeting of the European Association for the Study of Diabetes (EASD)
Liang-Hao Guo, Peter AchenbachDiabetes Research Institute, Munich, Germany.
Clinical type 1 diabetes is preceded by autoimmune destruction of the pancreatic beta-cells. However, progression to disease is not uniform. One challenge facing current diabetes research is therefore to identify biomarker profiles that accurately reflect the individual stage of type 1 diabetes pathogenesis and develop new techniques to distinguish between these profiles and associated diabetes risks. This report highlights some of the recent studies on diabetes biomarkers, with a particular focus on zinc transporter ZnT8, presented at the EASD meeting in September 2008 in Rome, Italy.
Keywordstype 1 diabetes · prediction · biomarker · autoantibody · zinc transporter · ZnT8 · SLC30A8 · metabolism · insulin resistance,.
Rev Diabet Stud